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In January 2003, an
siRNA Delivery Centre (www.sirna.dk)
has been established with support from the Danish Technical Research
Council. It was founded by a constellation of academic groups at the
Department of Molecular Biology, University of Aarhus, and at the
Department of Pharmaceutics, The Danish University of
 Pharmaceutical
Sciences, with inclusion of a large pharmaceutical company, H.
Lundbeck A/S - and Pipeline Biotech A/S.
What is siRNA?
By a phenomenon called
RNA interference (RNAi) 21 nucleotide small interfering RNAs (siRNA)
can elicit an effective degradation of specific mRNAs in human
cells. Since the specificity and efficiency of the RNAi approach in
“knock down” of genes is unprecedented, a renewed optimism in
development of drugs with high therapeutic potential has been
created. |
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